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American Foundation for
Donation & Transplantation

8154 Forest Hill Ave, Suite 3
Richmond, VA 23235
Phone: (804) 323-9890
Toll Free: (800) 543-6399
FAX: (804) 323-1300

American Foundation for Donation & Transplantation
Histocompatibility Specialist Course


The curricilum is designed for senior technologists and new laboratory directors involved in the day to day management and development of the histocompatibility laboratory. Applicants should have a background in immunology, immunogenetics and histocompatibility.


Program objective is to establish a structured curriculum leading to:

  • Raising the standards of practise in clinical histocompatibility testing.
  • Providing a fundamental educational program leading to ABHI Histocompatibility Specialist Certification (CHS).
  • Promoting excellence in clinical laboratory medicine.


Each student will receive a comprehensive course syllabus containing:

  • Lecture summaries.
  • References and bibliography.
  • Procedures with applications.


Course presentation will be in didactic and interactive discussion format. The curriculum focus is on histocompatibility testing:

  • Theory and principle.
  • Procedure.
  • Application.
  • Management.

Application Requirements

Tecgnologist in Histocompatibilty Testing, with a minimum of 3 years working experience and/or a formal course in immunology or genetics. Or applicant must be a new laboratory director.

  • Resume.
  • Active ASHI membership is recommended.
  • Pre-requisite reading completed.

Core Curriculum

  • Immunobiology.
  • Basic genetics and genetics of MHC.
  • Immunogloblins.
  • Immunology of the MHC.
  • Immunity.
  • Solid Organ Transplantation.
  • Bone Marrow Transplantation.
  • Platelet Immunology.
  • Complement.
  • Statistics in clinical and laboratory practice.
  • Immunosuppression.
  • Rejection mechanisms.
  • Serologic assays.
  • Crossmatching.
  • Antibody screening and evaluation.
  • Flow cytometry, crossmatching and antibody screening.
  • DNA methodologies and new techniques.
  • ELISA based technology.
  • Soluble antigen assay.
  • Quality assurance.
  • Biohazards and safety.
  • Cellular assays and immune response.
  • Laboratory management.
  • Population genetics.
  • Automation and computerization.
  • Regulatory agencies and transplantation.
  • Reimbursement issues.
  • Standards - ASHI, UNOS, CLIA and CMS.
  • Laboratory inspections.
  • Xenotransplantation.

AFDT currently has available both the Tissue Typing Reference Manual and the DNA Typing Technical Manual.

If you do not believe that you are on the mailing list for the specialist course please email us your address at skinner@amfdt.org.

Registration Form

Should you have questions, contact AMFDT at (804) 323-9890 or (804) 323-1300 FAX or by email, skinner@amfdt.org, or contact the Organizing Committee Chair.

Organizing Committee


Jean Heneghan, MS, CHS
Phone: 504-988-5259
Email:  jhenegh@tulane.edu

The course will have a limited number of registrants. Early registration is highly recommended, details to come.

General Information

Registration fee includes continental breakfast, breaks and lunch daily as well as welcome reception.
Hotel, transportation and other arrangements/costs are the student's responsibility.
The official language for the course is English.
The course is ABHI certified.

Please contact Arlene Skinner for additional information.
804 323-9890


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